Mrs Krabappel is fired from Springfield Elementary after Bart spikes her coffee, causing her to make a drunken fool of herself. She is replaced by a cool new teacher, Mr. Vaughn, who is a quick hit with the kids. Bart, however, struggles with the guilt and considers telling Principal Skinner the truth.

Eric visits the doctor’s office after getting some unsavory news from Drama about his latest fling. Ari investigates Terrance after he unexpectedly offers to sell Ari his share of his agency. Meanwhile, Turtle prepares for Jamie-Lynn’s departure and Drama’s emotions get the best of him during his audition for Melrose 2009.

Dexter mishandles crucial evidence in a case. His carelessness could come back to haunt him and impact Agent Lundy’s investigation into the latest Trinity Killer slayings.

In the sixth-season finale, Vince reluctantly answers a charity call from Matt Damon and LeBron James. Meanwhile, Ari tries to sell his business deal with Terrance to his wife; Drama considers a drastic career change; and Eric plans a rendezvous with Sloan.